Faculty and Student Accomplishments

Research in the Chemistry Department is a collaborative activity between faculty and students. UST chemistry students have one of the highest percentages of participation in research in the country, resulting in a strong presence at major research meetings like the Spring National Meeting of the American Chemical Society.  All of this is made possible by vibrant activity of our faculty and strong support from administration.  Here are some specific results of the work done by our faculty and students.

Active Funding:

  1. Fort, E. H. "Investigating the mechanism of aryl-alkyne cyclization of azaborine containing aromatics." Funded at $50,000. American Chemical Society Petroleum Research Fund. 
  2. LaPara, T.M. And Donato, J.J. "Does Triclosan Create Super Bugs During Wastewater Treatment?"  Total award funded at $380,000. Legislative-Citizen Commission on Minnesota Resources (LCCMR).
  3. Ojala, W. H.  "Solid-State Chemistry of the Nitrile Oxides" Funded at $65,000. American Chemical Society Petroleum Research Fund.
  4. Wammer, K.H. ;D.R. Stoll T.M. LaPara  “Antibiotics in Minnesota Waters: Phase 2, Mississippi River.” Funded at $203,000. Legislative-Citizen Commission on Minnesota Resources (LCCMR).
  5. Wammer, K. H. et al.  “Reversible photohydration in diene and triene steroids: A mechanism for unexpected persistence of unique, biologically active steroidal contaminants?” Funded at $394,746 National Science Foundation.
  6. Fort, E. H. “Investigating the mechanism of aryl-alkyne cyclization of azaborine containing aromatics.”  Funded at $50,000. American Chemical Society Petroleum Research Fund 
  7. Donato, J. J. “Shedding Light on the Mechanism of Action of an Enzyme that Confers Resistance to a Common Antimicrobial Agent” Funded at $48,120. Cottrell College Program of the Research Corporation for Science Advancement
  8. Prevette, L. E. Characterization of the Interaction Between Cell-Penetrating Compounds and Glycosaminoglycans”, Funded at $48,340. Cottrell College Program of the Research Corporation for Science Advancement

Publications in the last 2 years: (Undergraduate students underlined)

  1. Mabbott, G. A. “Teaching Electronics and Laboratory Automation with Microcontroller Boards,” J. Chem. Educ., 2014, 91(9), 1458–1463.
  2. Ojala, W. H.; Balidemaj, B.; Johnson, J. A.; Larson, S. N.; Ojala, C. R. “Molecular Symmetry and Fluorine-Containing Supramolecular Synthons as Structure-Differentiating Agents in Some ‘Bridge-Flipped’ Isomeric bis-Benzylideneanilines,” CrystEngComm, 2014, 16, 7226-7235.
  3. G. A. Mabbott, “An Automated Titrator Based on a Microcontroller: an Interfacing Exercise for Advanced Analytical Chemistry Students,” The Chemical Educator, 2014, 19, 96-101.
  4. Ippoliti, J. Thomas; Joshua Speros; Schewe, Scott R.; Warner, Robert W.; Dan Everson, “Polymers having lipophilic hydrocarbon and biodegradable polymeric segments” U.S. Patent 8653155 (2014)
  5. Wadle, J. J.; McDermott, L. B.; Fort, E. H.  "Microwave assisted synthesis of 10b-aza-10c-borapyrene" Tetrahedron Letters 2014, 55, 445 - 447.
  6. Liu, C. T.; Layfield, J. P.; Stewart III R. J.; French, J. B.; Hanoian, P.; Asbury, J. B.; Hammes-Schiffer, S.; Benkovic, S. J. J. Am. Chem. Soc. 2014, 136, 10349.
  7. Shade, A., Klimowicz, A.K., Spear, R.N., Linske, M., Donato, J.J., Hogan, C.S., McManus, P.S., Handelsman, J. (2013) Streptomycin application has no detectable effect on bacterial community structure in apple orchard soil. Appl Environ Microbiol. 2013 Aug 23. [Epub ahead of print].
  8. Layfield, J. P.; Hammes-Schiffer, S. Chem. Rev. 2013, 114, 3466.
  9. Wammer, K.H., A.R. Korte, R.A. Lundeen, J.E. Sundberg, K. McNeill, W.A.Arnold. (2013). Direct photochemistry of three antibacterials:  norfloxacin, ofloxacin, and enrofloxacin. Water Research, 47, 439-448.
  10. Boswell, P., Stoll, D., Carr, P., Nagel, M., Vitha, M., Mabbott, G. (2013) hplcsimulator.org an Advanced, Interactive High-Performance Liquid Chromatography Simulator and Instructor Resources, J. Chem. Educ.90 (2), 198–202.
  11. Ippoliti, J. Thomas and Kassekert, Luke “Overcoming Problems Incorporating NMR into the Organic Chemistry Lab”, Chapter 6, pp 83–90, in the ACS Symposium Series book: NMR Spectroscopy in the Undergraduate Curriculum (2013).
  12. T.C. Marsh, Z.M. Henseler and M.A. Klimstra  “Morphological Heterogeneity of Supramolecular G-DNA Polymers Derived from Guanine Rich Oligonucleotides” pp. 48-62, in Guanine Quartets: Structure and Application, (2013), 
  13. Layfield, J. P.; Hammes-Schiffer, S. J. Am. Chem. Soc. 2013, 135, 717.
  14. Fort, E. H.; Jeffreys, M. S.; Scott, L. T. (2012) Diels-Alder Cycloaddition of Acetylene Gas to a Polycyclic Aromatic Hydrocarbon Bay Region Chem. Commun.48, 8102-8104.
  15. Donato, J.J., Klimstra, M.A., Byrnes, J.R., White, R.J., and Marsh, T.C. (2012) The Introduction of Metagenomics into an Undergraduate Biochemistry Laboratory Course Yielded a Predicted Reductase that Decreases Triclosan Susceptibility in E. coli. DNA Cell Biol.  31(6), 968-73.
  16. Prevette, L.E.; Nikolova, E.N.; Al-Hashimi, H.M.; Banaszak Holl, M.M. (2012) Intrinsic Dynamics of Polymer-DNA Complexes: a Mechanism for DNA Release. Mol. Pharmaceutics9, 2743-2749.
  17. Gittins, P. J. and Twyman, L. J. (2012) Pyridine encapsulated hyperbranched polymers as mimetic models of haeme containing proteins, that also provide interesting and unusual porphyrin-ligand geometries, Chemical Communications 48, 154-156.
  18. William H. Ojala, Trina M. Arola, Ann M. Brigino, Jeremy D. Leavell, and Charles R. Ojala (2012) Competing Intermolecular Interactions in Some ‘Bridge-Flipped’ Isomeric Phenylhydrazones,; Acta Crystallographica, Section C:  Crystal Structure Communications 68,o270-o278. 
  19. Sloop, J.C., Shultz, D.A., Marcus, M.B., & Shepler, B. (2012), Linear Free Energy Relationships in Semiquinone Species and their Mn(II) and Cu(II) Complexes. J. Phys. Org. Chem., 25,  101- 109.
  20. Guino-o, M. A.; Torvisco, A.; Teng, W.; Ruhlandt-Senge, K. (2012) Alkaline earth metal di- and triphenylmethanides: Analysis of ion association modes.  Inorganica Chimica Acta, 389, 122-130.
  21. Guino-o, M. A.; Zureick, A. H.; Blank, N. F.; Anderson, B. J.; Chapp, T. W.; Kim, Y.; Glueck, D. S.; Rheingold, A. L. (2012) Synthesis and Structure of Platinum Bis(phospholane) Complexes Pt(diphos*)(R)(X), Catalyst Precursors for Asymmetric Phosphine Alkylation. Organometallics, 31, 6900-6910.
  22. Fort, E. H.; Scott, L. T. (2012) Facile Air-Oxidation of Large Aromatic Hydrocarbon Bay Regions to Bay Region Quinones. Predicted Oxygen-Sensitivity of Hydrogen-Terminated Carbon Nanotubes Org. Biomol. Chem.,  10, 5747-5749. 

Presentations in the last 12 months: (Undergraduate students underlined)

 

  1. Ojala, W. H.; Lystad, K. M.; Smieja, J. M.; Fermanich, J. M.; Ojala, C. R. “Nitrile-Halogen Interactions in Some Bridge-Flipped Isomeric Benzylideneanilines,” 23rd Congress and General Assembly of the International Union of Crystallography, Montreal, Canada, August 5-12, 2014.
  2. Wammer, K. H.; Anderson, K.C.; Erickson,P. R.; Kliegman, S.; McNeill, K.; Cwiertny, D. M.; Kolodziej, E. P. "Environmental Photochemistry of Altrenogest” EmCon 2014:  Fourth International Conference on Occurrence, Fate, Effects, & Analysis of Emerging Contaminants in the Environment, Iowa City, IA, August 19-22, 2014.
  3. Layfield, J. and Hammes-Schiffer, S. "Probing the Changing Electrostatic Environment Along the Catalytic Cycle of Dihydrofolate Reductase Using Nitrile Probes” Atomic and Molecular Interactions Gordon Research Conference, Easton, MA July 2014.
  4. Wammer, K. H. and Moffatt, M. E.  “Quantifying bacterial resistance to antibiotics in Minnesota surface waters,” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  5. Wammer, K. H. and Kapla, J. M. “Quantifying cultivable antibiotic-resistant bacteria in surface waters” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  6. Ippoliti, J. T.; and Zamulko, O. Y.  “Synthesis of a novel isoxazolinone,” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  7. Ippoliti, J. T.; and Sirianni, M. D.  “Tetrasubstituted furans from diarylpropargylic alcohols,” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  8. Ippoliti, J. T.; and Frommelt, M. A. “Kinetics of curing in polyaspartic coatings,” Abstracts of Papers 247th ACS National Meeting, Dallas, TX March 2014.
  9. Ippoliti, J. T.; and Mages, S. M. “Synthesis of a novel small molecule to trigger cancer cell death,” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  10. Ippoliti, J. T.; and Kummer, R. L.  “Synthesis of a topologically designed antibacterial compound” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  11. Ojala, W. H. and Herlitzke, B. J. “Solid-state intermolecular interactions in 3-chlorobenzaldoxime and 3-fluorobenzaldoxime: Hydrogen bonding vs. halogen bonding” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  12. Guino-o, M. A.; Folstad, M. J.; Kremer, D. M.  “Investigation of novel pincer ligands to sensitize lanthanide(III) luminescence,” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  13. Guino-o, M. A. and Talbot, M. O.  “Investigation of the amount of hydrogen gas produced by asymmetric triazolylidenes in the nickel-catalyzed dehydrogenation of ammonia-borane” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  14. Prevette, L. E. and Mueller, K. G.“DNA structure affects binding to polycationic delivery agents,” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  15. Prevette, L. E. and Smith, R. J. “Polyethylene glycol conjugation ratio and molecular weight affect polyethylenimine binding to DNA,” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  16. Prevette, L. E. and Benish, N. C. “Cell penetrating compounds selectively bind vesicles composed of anionic lipids,” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  17. Prevette, L. E. and Braden, K. J.“Charge density and stereochemistry affect the interaction of cell-penetrating compounds with glycosaminoglycans” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  18. Marsh, T. C. and Flood, B. M.  “G-wires are highly resistant to a broad spectrum of nucleases”Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  19. Ippoliti, J. T.; Kummer, R. L.; Zamulko, O. Y.;  Vinnik, V. “Synthesis of topologically designed compounds,” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  20. Prevette, L. E.; Braden, K. J.; Schoenecker, A. R.; Benish, N. C. “Structure affects the interactions of cell-penetrating compounds with cell-surface glycosaminoglycans and lipid vesicle model membranes.” Abstracts of Papers, 247th ACS National Meeting, Dallas, TX March 2014.
  21. Mabbott, G. A. "Microcontrollers in the Analytical Chemistry Teaching Lab" Abstracts of Papers, 2014 Pittcon Conference, Chicago, IL March 2014.
  22. Malone-Povolny, M. and Mabbott, G. "Development of a SERS Technique for the Quantitative Analysis of Bidentate Compounds" Abstracts of Papers, 2014 Pittcon Conference, Chicago, IL March 2014.
  23. Ippoliti, J.T., Frommelt, M. “Kinetics of Model Amine Compounds with Cyclohexyl Isocyanate”  Bayer MaterialScience, Pittsburgh, PA   January 23, 2014

  24. Wammer, K. H.; Moffatt, M. E.; Beck, E. W.; Burch, T. R.; LaPara, T. M. "Antibiotics and antibiotic resistance in a river impacted by agricultural and municipal inputs" Abstracts of Papers, 246th ACS National Meeting, Indianapolis, IN September 2013.