Immunology

May 9, 2010 / By: Jill M. Manske, PH.D.

Professional Interests

My broad research interest centers on the intersection between immunology, infectious disease, and community health.  Currently, we are collaborating with the University of Minnesota’s Center for Infectious Disease Research and Policy (CIDRAP) on projects related to influenza, influenza vaccine and science policy.
In addition, we have an ongoing (three year) project performing surveillance of Borrelia burgdorfei, the Lyme disease agent, in small mammals at Macalester College’s Katherine Ordway Natural History Study. This project involves a field component (animal trapping) followed by PCR analysis of tissue samples for presence of the specific disease-causing agent.

Current Projects

Recent projects that have been presented by students as published abstracts or in local, unpublished research symposia.  Student names are in bold.

M. Mertens and G. Rutledge.  Development of Flow Cytometric Methods for Immunology Research and Implementation into Biology Curriculum. University of St. Thomas Undergraduate Research Symposium.  OEC Auditorium.  September 25, 2002.

S.E. Hanson and A. Gray.  Substance P Mediated Protection of Tumor Establishment: The Role of NK Cells.  Journal of the Minnesota Academy of Science.  April 2001.

S.E. Hanson and J.M. Manske  The Effect of Substance P on Anti-Tumor Immunity in Mice.  Proceedings of the National Council on Undergraduate Research. 2000.

S.E. Hanson and J.M. Manske  The Effect of Substance P on Anti-Tumor Immunity in Mice.  Presented at: Sigma Xi Scientific Research Society’s International Annual Meeting.  November 6, 1999.  Minneapolis, MN.

L. Bollmeir and  K Ostergaard:  The effect of anti-NK antibody on NK numbers in mice: a model for studies of tumor growth.  UST Summer Research Poster Session.  Owens Science Hall. August, 2000.

S.E. Hanson:  A Study of One Interaction between the Nervous System and the Immune System:  The Effect of Substance P on Anti-Tumor Immunity of Mice. Society for Neuroscience,  Faculty for Undergraduate Neuroscience (FUN) Student Poster Session.New Orleans.  November 2000.

Manske, J.M., Hilson, N.A., Kinneberg, K.M., Moravec, M.T., Sullivan, E.L. and Rudolph, S.J.  The Effect of Substance P on Cytokine Secretion from Murine Bone Marrow Stromal Cells. J. Allergy and Clinical Immunol.  99:1, S56. 1997.

Manske, J.M., and Sullivan, E.L.  The Effect of Substance P on M2-10B4 Murine Bone Marrow Stromal Cells.  FASEB J., 10:6, A1073, 1996.

E.L. Sullivan and J.M. Manske The Effect of Substance P on M2-10B4 Murine Bone Marrow Stromal Cells.  Journal of the Minnesota Academy of Science 60:7 1996.

Publications & Presentations

Manske, J.M. (2010). “First, Do No Harm: The Role of Sustainability in the Education of Health Professionals.  Journal of Sustainability Education.

Chaplin, S.B. and Manske, J.M. A Theme Based Approach to Teaching Non-Majors Biology. Journal of College Science Teaching. In Press.

Manske, J.M. and Hanson, S.E.* Substance P-Mediated Immunomodulation of Tumor Growth in a Murine Model. Neuroimmunomodulation. 12(4): 201 ­10. 2005.

Manske, J.M.  Students with Disabilities: Unique Challenges and Opportunities for Science and Math Programs.  Council on Undergraduate Research Quarterly.  September.  27-31. 2001.

Manske, J.M. and Chaplin, S.B.  Integration of Undergraduate Research into the Teaching Curriculum at the University of St. Thomas.  Council on Undergraduate Research Quarterly.  September.  40-42.  2000.

Chaplin, S.B., Manske, J.M., and Cruise, J.L.  Introducing Freshmen to Investigative Research - A Course for Biology Majors at Minnesota’s University of St. Thomas.  Journal of College Science Teaching.  March/April.  347-350.  1998.

Manske, J.M., and Serie, J.R.   Alternatives to the Research University:  Immunologists in Primarily Undergraduate Institutions (PUI’s).  American Association of Immunologists Newsletter.  November/December.  6-10. 1997.

Sullivan, E.L. and Manske, J.M. The Effect of Substance P on M2-10B4 Murine Bone Marrow Stromal Cells.  In: Proceedings of the Tenth National Conference on Undergraduate Research, III. ed: R.D. Yearout.  University of North Carolina, Asheville. pp: 373-1377.  1996.

Manske, J.M., Sullivan, E.L., and Andersen, S.A.  Substance P Mediated Stimulation of Cytokine Levels in Cultured Murine Bone Marrow Stromal Cells. In: The Immunobiology of Proteins and Peptides, VIII. ed: M.Z. Atassi and G.S. Bixler, Jr.  Plenum Press, Inc., New York. pp. 53-64, 1995.

Presentations at national meetings:

Manske, J.M. and Monroe, J.  Developing Investigative Laboratory Courses in Biology.  Council on Undergradute Research Ninth National Conference.  New London, CT.  June 2002.

Manske, J.M and Osborn, J.  Using Your Courses to Feed Your Research Program. Council on Undergradute Research Ninth National Conference.  New London, CT.  June 2002.

Manske. J.M.  Research with Undergraduates:The Funding Challenge. Experimental Biology.  2001.  Orlando, Fl.

Manske, J.M.  The effect of Substance P on anti-tumor immunity in mice.  Tenth International Symposium of the Immunobiology of Proteins and Peptides. September, 2000.  Tahoe City, Ca.

Manske, J.M.  Three Models for Teaching Investigative Laboratories in Immunology to Undergraduates.  FASEB J.  14, 6.  A925.  2000.

Manske, J.M. So you want to work with Undergraduates?  Experimental Biology 2000.  May, 2000, Seattle, WA.

Manske, J.M.  How to Use Your Courses to Feed Your Research Program. The National Conference on Undergraduate Research.  June 22-24, 2000,  Wooster, Ohio.

Student Researchers

Current Students:

  • Lucas Brand
  • Alisha Duffy
  • Nhan Huynh
  • Christine Spampinato